Tryptophan Metabolism in Gut Microbes and Brain Axis

Targeting Microbiota 2021 Wei yun

Prof. Wei-Yun Zhu from College of Animal Science and Technology, Nanjing Agricultural University, China will join the Targeting Microbiota 2021 congress which will be held on October 20-22, 2021 and will provide a talk concerning "Tryptophan Metabolism in Gut Microbes and Brain Axis".

Prof. Zhu confirms that the bilateral communication network between the gastrointestinal (GI) tract and the central nervous system is regards as the gut-brain axis (GBA). Tryptophan is important for the growth and health of the animal and humans, and its microbial metabolism affects the interaction between gut microbiota and the GBA. By employing intestine cannulated pig model and adopting hindgut microbiota-targeting approaches either using antibiotics or increasing carbohydrate level, together with mechanistic studies in mice and neuronal cells, she demonstrates that tryptophan, and also another aromatic amino acid tyrosine, circulating in the gut, blood and brain, act as mediators between hindgut microbiota and brain neurochemistry. 


Targeting Microbiota 2021 Congress
October 20-22, 2021 - Paris, France & Online