Drinking Refined Deep-Sea Water: Impact on Gut Ecosystem & Intestinal Health

News Release, International Society of Microbiota, France – April 6, 2022

World health trends are focusing on a balanced food and beverage intake for healthy life. Refined deep-sea water (RDSW), obtained from deep-sea water collected offshore in Muroto (Japan), is mineral-rich drinking water.

Knowing that drinking RDSW improves human gut health, Takeuchi et al, analyzed the effect of drinking RDSW on the gut ecosystem to understand this effect.

In a randomized double-blind controlled trial, ninety-eight healthy adults were divided into two groups: RDSW or mineral water (control).

The participants consumed 1 L of either water type daily for 12 weeks.
A self-administered questionnaire and stool and urine samples were collected through the intervention.

The following results were determined: fecal biomarkers of secretory immunoglobulin A (sIgA), five putrefactive products, and nine short-chain-fatty-acids (SCFAs) as the primary outcomes; and three urinary isoflavones and the questionnaire as secondary outcomes.

In post-intervention in the RDSW group, we found increased concentrations of five SCFAs and decreased concentrations of phenol and sIgA .
The multiple logistic analysis demonstrated that RDSW significantly affected two biomarkers (acetic and 3-methylbutanoic acids) of the five SCFAs mentioned above.
The concentrations of urinary isoflavones tended to increase in post-intervention in the RDSW group. Constipation was significantly alleviated in the RDSW group (94%) compared with the control group (60%).

In conclusion, drinking RDSW was found to improve the intestinal environment by increasing fecal SCFAs and urinary isoflavones, which leads to broad beneficial effects in human.

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